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研究人員測試殺死傳播瘧疾的蚊子的真菌

kira86 于2019-06-25發布 l 已有人瀏覽
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蚊子傳播的疾病是導致非洲國家布基納法索兒童死亡的主要原因,馬里蘭大學研究人員正在測試一種可以通過結出殺死蚊子的真菌。
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Researchers Test Fungus That Kills Malaria Mosquitos

研究人員測試殺死傳播瘧疾的蚊子的真菌

According to the severe malaria observatory, the mosquito-borne disease is the leading cause of child mortality in the African nation of Burkina Faso.It’s a loss no parent should have to suffer.“Losing a child was really painful for me or for any parent for that matter. So if we can find the solution against this disease which killed my child, other people we will think that they should do everything to eradicate this disease. They should help us. We are hoping we are happy without further prices gone.More than half of the world’s population is at risk of contracting the disease but it’s a unique problem in Africa and that’s where University of Maryland researchers are testing a fungus that kills mosquitoes on contact.“We took a gene from a spider and we put that spider gene which encodes an insect selective toxin. We put that gene into the fungus under the control of a promoter and the promoter is the on/off switch of a gene so under the control of this promoter which only turns on in insect blood.” The fungus works quickly and effectively on malaria carrying mosquitoes the moment it comes in contact with the insects.

根據嚴重瘧疾觀察站的數據,蚊子傳播的疾病是導致非洲國家布基納法索兒童死亡的主要原因。沒有父母應該承受這種損失。失去一個孩子對我或任何父母來說都是非常痛苦的。所以,如果我們能找到治療這個殺死我孩子的疾病的方法,其他人,我們會認為,他們應該盡一切努力根除這個疾病。他們應該幫助我們。我們希望不再付出代價,我們會很高興。世界上一半以上的人口面臨感染這種疾病的風險,但這在非洲是一個特有的問題,馬里蘭大學的研究人員在那里正在測試一種真菌,這種真菌可通過接觸殺死蚊子。我們從蜘蛛身上提取了一個基因,然后把這個蜘蛛基因編碼成一種昆蟲選擇性毒素。我們把這個基因放進一個啟動子控制的真菌中,啟動子是一個基因的開關,所以在這個啟動子的控制下,這個啟動子只在昆蟲血液中啟動。”這種真菌一旦接觸到攜帶瘧疾的蚊子,就會迅速有效地對它們起作用。

“Out of the box if they land anywhere on the outside of a mosquito they’ll recognize that they’re on a mosquito and they’ll burrow their way into the mosquito.”In tests once the fungus was introduced into a mosquito population the mosquitoes were gone in a month but success in the lab doesn’t mean success in the field so the team is testing their mosquito killing fungus in Burkina Faso with the help of researchers there.Using raw meat, the team attracts mosquitoes into these test rooms.Once inside they rest on a black cloth that has been treated with the fungus, the results are swift.“Well, basically within two generations we’ve killed 99 percent of the mosquitoes so we caused the mosquito population to collapse.”The researchers say that the dramatic results of their test and using their treatment belong with insecticides could have a big impact on fighting malaria and also can be adapted to fight other diseases like Zika or dengue.

當從盒子里出來,如果它們落在蚊子外面的任何地方,它們就會意識到它們落在蚊子身上,它們會鉆入蚊子體內。”在測試中,一旦真菌被引入蚊子種群,蚊子在一個月內就消失了,但實驗室的成功并不意味著在該領域的成功,因此研究小組正在布基納法索的研究人員的幫助下在那里測試他們的殺蚊真菌。研究小組使用生肉將蚊子吸引到這些試驗室,一旦蚊子進入試驗室,它們就落在用真菌處理過的黑布上,結果很快就會出來。嗯,基本上在兩代之內,我們已經殺死了百分之九十九的蚊子,所以我們使蚊子數量的暴跌。研究人員說,他們測試和使用殺蟲劑治療的激動人心的結果可能對防治瘧疾產生重大影響,也可以適應于防治其他疾病,如齊卡或登革熱。

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